Overview
Cellular aging and metabolism are deeply interconnected, shaping longevity, health, and disease. Cellular metabolism drives essential biochemical processes, while aging is characterized by a progressive decline in function and an increased risk of age-related diseases, including neurodegenerative disorders, cardiovascular disease, diabetes, and cancer.
A key player in this process is cellular senescence, a state of irreversible cell cycle arrest that promotes chronic inflammation and tissue dysfunction through the senescence-associated secretory phenotype (SASP). While senescence serves as a protective mechanism against uncontrolled cell growth, it paradoxically contributes to cancer and other diseases by fostering a pro-inflammatory and degenerative environment.
Metabolic disturbances, including oxidative stress, mitochondrial dysfunction, and DNA damage, accelerate senescence, impair cellular repair mechanisms, and drive the progression of age-related diseases. Additionally, stem cells, which are essential for tissue maintenance and regeneration, experience age-related decline due to metabolic shifts, reducing their ability to repair damage and contributing to both degenerative conditions and malignancies.
During this meeting, we will explore the intricate connections between metabolism, senescence, mitochondria, DNA stability, stem cell biology, cancer, and age-related diseases. By bringing together leading experts, this symposium aims to advance discussions on the latest strategies to modulate aging, enhance tissue regeneration, and develop innovative therapies to combat age-related diseases and cancer, ultimately promoting healthier aging and longevity.
Speakers
CIMUS-CNB-CSIC. Universidade de Santiago de Compostela.
Santiago de Compostela, Spain
IBB-Institute for Bioengineering and Biosciences.
Technical University of Lisboa.
Lisboa. Portugal
University of Edinburgh.
Edinburgh. United Kindgom
CIMUS. Universidade de Santiago de Compostela.
Santiago de Compostela. Spain
Universidad Autónoma de Madrid.
Madrid. Spain
University of Lausanne.
Switzerland
Translational Medical Oncology (ONCOMET)
Santiago de Compostela Research Institute (IDIS).
Santiago de Compostela. Spain
Universidad de Valencia.
Valencia. Spain
IBIS. Universidad de Sevilla.
Sevilla. Spain
Center for Applied Medical Research (CIMA).
Navarra. Spain
CSIC. Instituto de biomedicina y biotecnología de Cantabria. Santander. Spain
Universidad Cardenal Herrera-CEU
Valencia. Spain
Josep Carreras Leukaemia Research Insitute Foundation, IJC.
Barcelona. Spain
University of Southampton.
Southampton. United Kingdom
Josep Carreras Leukaemia Research Institute, IJC.
Barcelona, Spain
_Scientific committee
Laboratory of Cellular Senescence, Cancer and Ageing
Health Research Institute of
Santiago de Compostela (IDIS), Spain
Health Research Institute of Santiago de Compostela (IDIS)
Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Cellular Therapy and Regenerative Medicine Group
CICA-INIBIC
Universidade da Coruña, Spain
Cartilage Biology Unit, Rheumatology Research Group
Biomedical Research of A Coruña (INIBIC), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Gene and Cell Therapy Research Group (G-CEL)
Interdisciplinary Center for Chemistry and Biology (CICA)
Universidade da Coruña, Spain
Laboratory of Glia-Neuron Interactions in the Control of Hunger
Achucarro Basque Center for Neuroscience
Leioa, Spain
Scientific committee
CIMUS-CNB-CSIC. Universidade de Santiago de Compostela.
Santiago de Compostela, Spain
Prof. Susana Sangiao Alvarellos
Metabolic diseases, cancer and aging (MetCaEn)
CICA-INIBIC.
Universidade da Coruña, Spain.
A Coruña, Spain
Cartilage Biology Unit, Rheumatology Research Group.
Biomedical Research of A Coruña (INIBIC).
A Coruña, Spain
Gene and Cell Therapy Research Group (G-CEL).
Interdisciplinary Center for Chemistry and Biology (CICA).
Universidade da Coruña, Spain.
A Coruña, Spain
Dr. M. Carmen de Andrés González
Epigenetic Unit, Rheumatology Research Group.
Biomedical Research of A Coruña (INIBIC).
A Coruña. Spain
Cardiovascular Research Center.
Massachusetts General Hospital, Harvard Medical School.
Boston, USA
Medical Oncology Department, Reserch Unit,
University Hospital Lucus Augusti.
Lugo, Spain
Dr. José A. Rodriguez Navarro
Universidad Complutense de Madrid.
Madrid, Spain
European Cancer Stem Cell Research Institute.
Wales, United Kingdom
Pharmacology Unit- Department of Pharmacology.
Toxicology and Therapeutic Chemistry.
Faculty of Pharmacy and Food Sciences.
University of Barcelona.
Barcelona, Spain
Dr. Mª Elena Rendueles García
Metabolic diseases, cancer and aging (MetCaEn)
CICA-INIBIC.
Universidade da Coruña, Spain.
A Coruña, Spain
Metabolic diseases, cancer and aging (MetCaEn)
CICA-INIBIC.
Universidade da Coruña, Spain.
A Coruña, Spain
Blizard Institute. Queen Mary University of London.
London, UK
Lung Cancer Early Detection Group.
Cambridge Cancer Centre.
Cambridge, United Kingdom
_Scientific committee
Laboratory of Cellular Senescence, Cancer and Ageing
Health Research Institute of
Santiago de Compostela (IDIS), Spain
Health Research Institute of Santiago de Compostela (IDIS)
Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Cellular Therapy and Regenerative Medicine Group
CICA-INIBIC
Universidade da Coruña, Spain
Cartilage Biology Unit, Rheumatology Research Group
Biomedical Research of A Coruña (INIBIC), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Gene and Cell Therapy Research Group (G-CEL)
Interdisciplinary Center for Chemistry and Biology (CICA)
Universidade da Coruña, Spain
Laboratory of Glia-Neuron Interactions in the Control of Hunger
Achucarro Basque Center for Neuroscience
Leioa, Spain
Agenda
21st July
Moderator: Prof. María C. Arufe
9.30
Opening the event
10.00
SIRT7 at the crossroad between metabolic homeostasis and epigenetics in aging
Alejandro Vaquero
Josep Carreras Leukaemia Research Institute, IJC.
Barcelona. Spain
10.45
Innovating the manufacturing of stem/progenitor cell-based therapies
Cláudia Lobato da Silva
IBB-Institute for Bioengineering and Biosciences. Technical University of Lisboa. Lisboa. Portugal
11.30
RNA-mediated regulation of cellular senescence
Marta Montes
Center for Applied Medical Research (CIMA).
Navarra. Spain
12.15
Coffee Break and Poster Exhibition
Moderator: Dr. M. Carmen de Andrés González
12.45
Primary cilia dynamics in senescence and ageing
Sofía Ferreira
University of Edinburgh. Edinburgh
13.30
SASP in neurodegenerative diseases
Diego Gómez Nicola
University of Southampton.
Southampton. United Kingdom
14.15
Lunch Break
17.00
Flash Talks
18.00
Single Cell Analysis from cell sorting to mRNA and protein profiling. BD BioSciences-Lifesciences
18.30
Flash Talks
19.00
Satellite Session
_Scientific committee
Laboratory of Cellular Senescence, Cancer and Ageing
Health Research Institute of
Santiago de Compostela (IDIS), Spain
Health Research Institute of Santiago de Compostela (IDIS)
Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Cartilage Biology Unit, Rheumatology Research Group
Biomedical Research of A Coruña (INIBIC), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Gene and Cell Therapy Research Group (G-CEL)
Interdisciplinary Center for Chemistry and Biology (CICA)
Universidade da Coruña, Spain
22nd July
Moderator: Dr. Manuel Collado
9.30
Sex-specific molecular hallmarks leading to increased atherogenesis susceptibility in male mice with early aging
Fernando de la Cuesta
Universidad Autónoma de Madrid
Madrid. Spain
10.15
Effects of endothelial senescence on brain plasticity mediated by adult neurogenesis
Isabel Fariñas
Universidad de Valencia
Valencia. Spain
11.00
Generation of a safe mouse model for long-term in vivo hematopoietic partial reprogramming
Gabriela Desdín Mico
University of Lausanne.
Switzerland
11.45
Coffee Break and Poster Exhibition
Moderator: Prof. Susana Sangiao
12.30
RNA polymerase II in nucleolar stress
Daniel Gómez Cabello
IBIS. Universidade de Sevilla.
Sevilla. Spain
13.15
Reprogramming cancer, aging and obesity
Manuel Collado
CIMUS-IDIS-CNB-Universidade de Santiago de Compostela. Santiago de Compostela. A Coruña. Spain
14.00
Lunch Break
17.00
Flash Talks
19.00
Poster exhibition
_Scientific committee
Laboratory of Cellular Senescence, Cancer and Ageing
Health Research Institute of
Santiago de Compostela (IDIS), Spain
Health Research Institute of Santiago de Compostela (IDIS)
Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Cartilage Biology Unit, Rheumatology Research Group
Biomedical Research of A Coruña (INIBIC), Spain
Cellular Therapy and Regenerative Medicine Group (TCMR)
CICA-INIBIC
Universidade da Coruña, Spain
Gene and Cell Therapy Research Group (G-CEL)
Interdisciplinary Center for Chemistry and Biology (CICA)
Universidade da Coruña, Spain
23rd July
Moderator: Dr. Ana Rey Rico
9.15
Regulation of cellular senescence by lipid metabolism
Juan Carlos Acosta
CSIC. Instituto de Biomedicina y Biotecnología de Cantabria.
Santander. Spain
10.00
Nanoemulsions as versatile tools in cancer: From CTC support to targeted ovarian therapy
Ana Belén Davila Ibáñez
Translational Medical Oncology (ONCOMET)
Santiago de Compostela Research Institute (IDIS).
Santiago de Compostela. Spain
10.45
Targeting Cellular Aging: Natural Compounds Modulating Longevity Pathways
Eloy Bejarano
Universidad Cardenal Herrera-CEU
Valencia. Spain
11.30
Coffee Break and Poster Exhibition
Moderator: Dr. Mª Elena Rendueles García
12.00
Unravelling cellular senescence as a mechanism of tumour relapse in non-hodgkin lymphoma
Verónica Rodilla
Josep Carreras Leukaemia Research Institute, IJC.
Barcelona. Spain
12.45
MitoPhenomics of health and disease
Aurora Gómez-Durán
CIMUS. Universidade de Santiago de Compostela.
Santiago de Compostela. Spain.
13.30
Award to the best flash talk and poster
Participants:
PI/Postdoc/PhD students/Master students/Degree students/Public
Abstract Submission:
Send an email to contact@cams2025.com indicating:
-Title of work
-Authors and affiliation
-Abstract of work
Rules for presentations:
Flash talk: 10 minutes per talk
Download Flash Talks programme
Poster:
- Size: Landscape 70 x 50 cm.
- File Formats allowed: PDF, JPG, PNG
- Image Resolution: 300 ppp
Deadline:
Extended to 16th June 2025
Abstract submission
Organization
Cellular Therapy and Regenerative Medicine Group (TCMR).
CICA-INIBIC.
Universidade da Coruña.
A Coruña. Spain
Cellular Therapy and Regenerative Medicine Group (TCMR).
CICA-INIBIC.
Universidade da Coruña.
A Coruña. Spain
Assistance to organization:
Rocío Mato Basalo
PhD Student. TCMR Group. CICA-INIBIC
Universidade da Coruña. Spain
Sergio Lucio Gallego
PhD Student. TCMR Group. CICA-INIBIC
Universidade da Coruña. Spain
Cristina Varela Pombo
PhD Student. TCMR Group. CICA-INIBIC
Universidade da Coruña. Spain
Alba Ramil Bouzas
PhD Student. G-CEL & BioNanoChem Group CICA
Universidade da Coruña. Spain
Lama Berjawi
PhD Student. TCMR Group. CICA-INIBIC
Universidade da Coruña. Spain
Alba Iglesias Fente
PhD Student. G-CEL Group CICA
Universidade da Coruña. Spain
Junquera López Seijas
PhD Student. G-CEL Group CICA
Universidade da Coruña. Spain
Getting there
2A
Stop at Hospital de Oza.
6 min. walking
12-12A-17-22
Stop at Avda. da Pasaxe. Viaducto.
12 min. walking
Nearest Taxi stop: Hospital de Oza
Xubias de Arriba, 5, A Coruña
6 min. walking
CAMS 2025
21-23 July 2025
Facultade de Ciencias da Saúde
UDC Campus de Oza
15006 A Coruña
Galicia Spain
Funding entities
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